MR biophysics
Neuroimaging
Systems Neuroscience
a) the development of physiological and functional MRI techniques,
b) the investigation of biophysical and physiological sources of MRI signals (functional MRI, perfusion, diffusion, chemical exchange MRI), and
c) the application of neuroimaging techniques to systems neuroscience research.
Education
(Ph.D.) Physical Chemistry, Washington University St. Louis, MO
Journal Articles
(2024)
Interaction Between a High-Fat Diet and Tau Pathology in Mice: Implications for Alzheimer's Disease.
JOURNAL OF ALZHEIMERS DISEASE.
97,
1
(2023)
Whole-brain mapping of effective connectivity by fMRI with cortex-wide patterned optogenetics.
NEURON.
111,
111
(2023)
Parvalbumin interneuron activity drives fast inhibition-induced vasoconstriction followed by slow substance P-mediated vasodilation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
120,
8
(2022)
Improved laminar specificity and sensitivity by combining SE and GE BOLD signals.
NEUROIMAGE.
264,
1
(2022)
General-Purpose Ultrasound Neuromodulation System for Chronic, Closed-Loop Preclinical Studies in Freely Behaving Rodents.
ADVANCED SCIENCE.
34,
9
(2022)
Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
23,
20
(2022)
Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice.
CELL REPORTS.
40,
12
(2022)
Whole-brain perfusion mapping in mice by dynamic BOLD MRI with transient hypoxia.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM.
42,
12
(2022)
Theory of chemical exchange saturation transfer MRI in the context of different magnetic fields.
NMR IN BIOMEDICINE.
35,
11
(2022)
Neural mechanisms of pain relief through paying attention to painful stimuli.
PAIN.
163,
6
(2022)
Role of anterior cingulate cortex inputs to periaqueductal gray for pain avoidance.
CURRENT BIOLOGY.
32,
13
(2022)
Review and consensus recommendations on clinical APT-weighted imaging approaches at 3T: Application to brain tumors.
MAGNETIC RESONANCE IN MEDICINE.
88,
2
(2022)
Thrombin Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage Induced Neonatal Rats.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
23,
8
(2022)
Deep brain stimulation of the anterior nuclei of the thalamus can alleviate seizure severity and induce hippocampal GABAergic neuronal changes in a pilocarpine-induced epileptic mouse brain.
CEREBRAL CORTEX.
32,
24
(2022)
Dissection of brain-wide resting-state and functional somatosensory circuits by fMRI with optogenetic silencing.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
119,
4
(2022)
Protocol for mouse optogenetic fMRI at ultrahigh magnetic fields.
STAR Protocols.
3,
4
(2021)
Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI.
MAGNETIC RESONANCE IN MEDICINE.
87,
1
(2021)
Improvement of sensitivity and specificity for laminar BOLD fMRI with double spin-echo EPI in humans at 7 T.
NEUROIMAGE.
241,
-
(2021)
Characterization of brain-wide somatosensory BOLD fMRI in mice under dexmedetomidine/isoflurane and ketamine/xylazine.
SCIENTIFIC REPORTS.
11,
1
(2021)
Layer-dependent functional connectivity methods.
PROGRESS IN NEUROBIOLOGY.
207,
-
Conference Paper
(2015)
Mapping Layer-Specific Neural Activity in the Olfactory Bulb with fMRI.
Brain Conference 2015.
KOREA, REPUBLIC OF
(2015)
Neural Activity and the Hemodynamic Response.
NeuroFutures2015 Conference.
UNITED STATES
(2015)
Pre-clinical Neuroimaging.
The 3rd ICMRI & The 20th Annaual Scientific Meeting of KSMRM.
KOREA, REPUBLIC OF
(2015)
Functional imaging of single cell to whole brain.
IPIU2015(Image Processing & Image Understanding).
KOREA, REPUBLIC OF
(2014)
Physiological MR Imaging for Pre-clinical Research.
제1회 DGMIF 실험동물센터 심포지엄 Preclinical in vivo Imaging.
KOREA, REPUBLIC OF
(2014)
Non-invasive MR imaging of brain function and metabolism.
International Scientific Symposium _What technology can achieve to help public health in Korea and globally?.
KOREA, REPUBLIC OF
(2014)
Functional MRI: Spatial Localization.
4th SKKU-NU Annual Workshop on NANO/BIO/PLASMA at SKKU.
KOREA, REPUBLIC OF
(2014)
Longitudinal changes in resting state functional connectivity by cocaine in rhesus monkeys.
2014 Society of Neuroscience.
UNITED STATES
(2014)
Noninvasive Imaging of Brain for Neuroscience Research.
IBS-ROYAL SOCIETY Research Conference.
KOREA, REPUBLIC OF
(2014)
Chemical Exchange Saturation Transfer(CEST) Imaging of the Molecular Progression of Neuronal Loss in a Parkinson’s Disease Rat Model.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Contributions of excitatory and inhibitory neural activities to BOLD and CBV fMRI.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Effects of Chronic Ocular Hypertension and Hypotensive Drug Treatment on Ocular Physiology and Biotransport Using Dynamic Gadolinium-Enhanced MRI.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Effects of Chronic Ocular Hypertension on Microstructural Integrity of the Visual System Using Diffusion Tensor MRI.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
In Vivo Compressed Sensing fMRI Using Conventional Gradient-Recalled Echo and EPI Sequences.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Magic Angle Enhanced MR Microscopy of Fibrous Structures in Normotensive and Hypertensive Eyes Using T2, T2* and T1rho MRI.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Prediction of Complex MR Signals of a Single Vein: Potential Advancement to Measurement of Venous Oxygen Saturation and Diameter .
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Spatiotemporal Characterization of Neurodegeneration in the Visual System Upon Acute and Chronic Optic Neuropathies Using Diffusion Tensor MRI.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Spin-Lock MRI of Glucose and Deoxyglucose Concentration Changes in Brain.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Structural, Metabolic and Functional Relationships Between the Eye and the Brain in Glaucoma Using Multimodal MRI and Optical Coherence Tomograph.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
(2014)
Top Down Influence on the Visual Cortex of the Blind During Auditory Sensory Substitution.
The Joint Annual Meeting ISMRM-ESMRMB 2014.
ITALY
